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Glycaemic control among patients with Type 2 Diabetes Mellitus in Swaziland
$ 36.5
Description
Background: Diabetes is a common metabolic disease with increasing prevalence in Southern Africa. The study sought to determine whether fasting blood sugar (FBG), mean fasting blood sugar and postprandial glucose (PPG) correlated well with the glycated haemoglobin (Hba1c) as a measure of glycaemic control in adults with type 2 diabetes (T2DM). It also sought to determine overall control of blood pressure, lipids and weight. Methods: A cross sectional study was conducted at the Outpatients’ Department of Mankayane Government Hospital in Swaziland. 292 patients with T2DM were enrolled into the study. The inclusion criteria were; age ≥18 to ≤75years, FBG ≤6.5mmol/l (two recorded results) and stable treatment regimen in the preceding three months, no concomitant severe/ moderate anaemia or renal failure or use of dapsone in the previous three months. Results: The median age for study participants was 61 years, with a median duration of diabetes of 1 year. There was no significant correlation between HbA1c and the FBG (r = 0.07625, p = 0.1939). However, PPG and mean fasting blood glucose correlated with the HbA1c (r = 0.5447 and p < 0.0001 and r = 0.1154, p<0.05, respectively). Cardiovascular risk factors obesity, blood pressure, and total serum cholesterol were poorly controlled, while triglycerides were within target range. Conclusions: PPG predicted glycaemic control better than either FBG or mean fasting blood glucose, in patients with FBG within target range. Cardiovascular risk factors were generally not well controlled; thus, a holistic approach should be taken to ensure they are addressed adequately.