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Pharmacists need to conduct clinical research and case reports as drug experts. This time, we indicated a case report in which a pharmacist proposed a combination therapy of midodrine and droxidopa to a doctor for refractory hypotension in a patient with chronic heart failure. In addition, we showed the results of a retrospective study evaluating the efficacy of recombinant human soluble thrombomodulin, a therapeutic agent for disseminated intravascular coagulation.