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Description

Various naturally occurring phytochemicals exhibit anti-inflammatory activity and are considered to be potential drug candidates against inflammation-related pathological processes. Here, new flavonoid glycoside, kaempferol 3-O-α-¬[(6-P coumaroyl galactopyranosyl-O-β- (1→4)-O-α-rhamnopyranosyl-(1→4)]-O-α-rhamnopyranoside 1, in addition to five known flavonoid glycosides (2-6) kaempferol 3-O-[α- ¬rhamnopyranosyl-(1→4)-O-α-rhamnopyranosyl-(1→6)-O]-β- galactopyranoside (kaempferol 3-O-β-isorhamninoside) 2, quercetin 3-O- [(2,3,4-triacetyl-α-rhamnopyranosyl)-(1→6)-β-galactopyranoside 3, quercetin 3-O-[(2,4-diacetyl-α-rhamnopyranosyl)-(1→6)]-3,4-diacetyl-β- galactopyranoside 4, quercetin 3-O-[(2,4-diacetyl-α-rhamnopyranosyl)- (1→6)]-2,4-diacetyl-β-galactopyranoside 5, quercetin 3-O-[(2,3,4-triacetyl- α-rhamnopyranosyl)-(1→6)-3-acetyl-β-galactopyranoside 6 were isolated from bell pepper (Capsicum annum L.) fruits and tested for both antiinflammatory activity through cytokine production (TNF-α and IL-1β) and antioxidant activity through scavenging effect on 1,1-diphenyl-2- picrylhydrazyl (DPPH) assay.