Nano-Encapsulation Using Macrocyclic Carbohydrate Polymers (βcyclodextrins) of Periploca Angustifolia Extract
$ 36.5
Description
The nano-encapsulation of Periploca angustifolia phenolic extract using the macrocyclic carbohydrate polymers (β-cyclodextrins) is a most approach compared with other encapsulation methods. In this work, the β-Cyclodextrins-PAE complex stability has been evaluated by advanced analytical methods and techniques including HPLC, FTIR and XRD. The results showed that CdCl2 treatment caused a significant decrease in cell viability. The CdCl2-induced damage in the HepG2 cells were significantly ameliorated (p<0.001) by treatment of the PAE and β-Cyclodextrins-PAE complex. Thus, pretreatment with 100 µg.mL-1 of β-Cyclodextrins-PAE complex significantly protect HepG2 cells against cytotoxicity induced by cadmium exposure more effectively than PAE only. However, Cd-intoxication significantly (p<0.001) increased these enzymes activity.