Toward a cure – Advancing HIV/AIDs treatment modalities beyond antiretroviral therapy
$ 42.5
Description
The human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS) is a significant danger to global public health. HIV/AIDS remains a significant concern despite substantial progress in our understanding of the virus and the development of effective treatment protocols. This is particularly applicable in low- and middle-income nations where access to healthcare may be limited. Antiretroviral therapy (ART) plays an important role in the management of HIV/AIDS, having revolutionized patient care and significantly enhanced outcomes. Although ART has transformed HIV from a terminal condition to a manageable chronic illness, it does not constitute a cure. ART has some problems, like the development of drug-resistant strains, side effects, and difficulty in accessing in places with few resources. This shows how important it is to come up with new ways to treat HIV. Viral reservoirs, drug resistance, and the necessity for lifelong medication adherence are cited as reasons that new treatment options must be implemented without delay. In light of these challenges, it is imperative to investigate novel treatment modalities that could facilitate long-term viral control, reduce reliance on lifelong medication, and ultimately lead to an HIV cure. This book aims to explore the current frontiers of HIV/AIDS research and identify promising avenues that may lead to a cure. A comprehensive review of the literature was conducted, focusing on reputable databases including PubMed, Scopus, Web of Science, and others. A comprehensive literature review identified many therapeutic modalities, such as stem cell transplantation, immunotherapy, gene therapy, latency reversal agents (LRAs), and pharmacological vaccines. This article aims to elucidate the evolving landscape of HIV/AIDS management by combining contemporary research findings and addressing the complexities inherent in HIV/AIDS treatment. By acquiring a comprehensive awareness of existing challenges and opportunities, we can avoid them and adopt a more effective and sustainable strategy for addressing this ongoing global health crisis.