Book

Experimental Approaches to Detect EBV Adaptive Immunity is a timely and valuable resource for researchers investigating the complex relationship between Epstein–Barr virus (EBV), adaptive immunity, and autoimmune or neurological diseases, particularly multiple sclerosis. The book provides a comprehensive overview of modern technologies for characterizing EBV-specific immune responses, including immunofluorescence, MHC multimer analysis, ELISpot, T-cell receptor sequencing, and PhIP-Seq. A major strength is its combination of theoretical principles, detailed experimental protocols, and practical guidance, enabling readers to understand both the applications and limitations of these complementary approaches. By integrating conventional immunological assays with high-throughput immune-repertoire and antigen-discovery technologies, the book demonstrates how EBV-specific immune profiling can advance our understanding of disease mechanisms, biomarker discovery, therapeutic development.